Slide 1
Featured at
ASCO 2021:
advanced melanoma
Slide 2
Slide 3
Breakthrough long-term survival in
recurrent GBM
Slide 4
PVSRIPO
isn’t
just another viral immunotherapy
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Learn more about the LUMINOS-102 study design in advanced melanoma

See preclinical data and ongoing melanoma trial featured at ASCO 2021

Review phase 1 results presented at SITC and published in the JITC

Visit the LUMINOS-102 study protocol page on clinicaltrials.gov

Learn more about the LUMINOS-102 study design in advanced melanoma

See preclinical data and ongoing melanoma trial featured at ASCO 2021

Review phase 1 results presented at SITC and published in the JITC

Visit the LUMINOS-102 study protocol page on clinicaltrials.gov

LUMINOS-102-transparent-bg-white

Actively recruiting phase 2 trial of PVSRIPO for advanced, PD-1–refractory melanoma

PVSRIPO +/- anti–PD-1 therapy in advanced melanoma following PD-1/L1 failure

The LUMINOS-102 trial is designed to build on the results of the phase 1 trial of PVSRIPO, in which clinical responses were observed in injected and noninjected tumors in patients with unresectable, treatment-refractory melanoma.

See an overview of LUMINOS-102

Featured presentation at ASCO 2021: review data from a mouse model of advanced melanoma

Lauren Neighbours, PhD, RAC, from Istari Oncology reviews key findings from a preclinical study of murine PVSRIPO in a mouse model of advanced melanoma and what the findings mean for the ongoing LUMINOS-102 phase 2 clinical study of PVSRIPO with and without anti–PD-1 therapy in unresectable advanced melanoma.

Featured presentation at ASCO 2021: review data from a mouse model of advanced melanoma

Lauren Neighbours, PhD, RAC, from Istari Oncology reviews key findings from a preclinical study of murine PVSRIPO in a mouse model of advanced melanoma and what the findings mean for the ongoing LUMINOS-102 phase 2 clinical study of PVSRIPO with and without anti–PD-1 therapy in unresectable advanced melanoma.

LUMINOS-102 melanoma poster

Review the phase 1 results

Download the poster and peer-reviewed publication in the Journal for ImmunoTherapy of Cancer with the results of the phase 1 PVSRIPO trial in unresectable, treatment-refractory melanoma.

Review the phase 1 results

LUMINOS-102 melanoma poster

Download the poster and peer-reviewed publication in the Journal for ImmunoTherapy of Cancer with the results of the phase 1 PVSRIPO trial in unresectable, treatment-refractory melanoma.

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